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Simeox Academy


About this training programme

Theoretical and practical training on the Simeox device.

Training objectives

The objective of this training is to fully understand the operating principle of the Simeox device and its clinical applications. A large part is dedicated to the practice to facilitate the proper implementation of Simeox therapy.

Methodology and pedagogy

This training is divided into 4 modules: 1. Physiology and pathophysiology reminders concerning obstructive respiratory pathologies and the role of respiratory physiotherapy in their management, 2. The theory of the Simeox device, 3. The handling of the device, and finally 4. The clinical practice. This teaching progamme includes numerous illustrations including 3D and 2D visualizations for a better understanding of the pathophysiology of chronic respiratory pathologies, and the functioning of the Simeox device. Clinical practice will be illustrated with patients (a healthy patient, a cystic fibrosis patient and a COPD patient).


This training is open to healthcare professionals (physiotherapists, physicians, nurses).

Training program


It is important to follow all 4 modules of this training programme in the proposed order, to have a good understanding of the Simeox device and thus to be able to use it optimally.

Reminders of Physiology, Physiopathology and notions of Respiratory Physiotherapy

This theoretical part begins with reminders on the normal respiratory pump and the pathological respiratory pump, after which a reminder on rheology and mucus behavior is given. Finally, some notions on respiratory physiotherapy are reviewed.

Simeox device: the theory

The theory about the Simeox device consists of 6 sub-parts.

  • An introduction about Simeox
  • Indications and contraindications to the use of the Simeox device
  • For which diseases Simeox is intended
  • The principle of use with a video on a test bench showing the Simeox effect.
  • The benefits expected from the use of the Simeox device
  • Clinical data available to date

Handling the Simeox device

This part is about the instructions for handling the Simeox device. We go through all the steps allowing the optimal use of the Simeox: connection, installation, assembly of the exhalation kit, settings and visual indicator, management of the remote control, progress of the session, end of session, cleaning of the Simeox device and the expiratory circuit.

SIMEOX DEVICE: Clinical practice

This section will give you all the information and advice you need to properly use Simeox in practice so that your patients can fully benefit from it. Particular attention is paid to the first session for each new patient, for which you will have to spend more time than usual. This time provided at the first session will ensure patient adherence and ensure the good results you will achieve later with Simeox. This part is mainly illustrated with patients (cystic fibrosis patient and COPD patient) in real conditions.

Scientific references

  • Goblet cell hyperplasia and epithelial inflammation in peripheral airways of smokers with both symptoms of chronic bronchitis and chronic airflow limitation. Saetta M, Turato G, Baraldo S, Zanin A, Braccioni F, Mapp CE, Maestrelli P, Cavallesco G, Papi A, Fabbri LM. Am J Respir Crit Care Med Vol 161. pp 1016–1021, 2000
  • COPD and inflammation: Statement from a French expert group. How to treat inflammation ? Roche N, Devillier P, Aguilaniu B, Escamilla R, Wallaert B, Burgel PR, Berger P, Brillet PY, Chambellan A, Chanez P, Chaouat A, Louis R, Mal H, Marthan R, Muir JF, Pérez T, Similowski T, Aubier M. Rev Mal Respir. 2011 Apr;28(4):427-42. doi: 10.1016/j.rmr.2010.08.017.
  • Airway gland structure and function. Jonathan H. Widdicombe and Jeffrey J. Wine. Physiol Rev. 2015 Oct;95(4):1241-319. doi:10.1152/physrev.00039.2014.
  • The Nature of Small-Airway Obstruction in Chronic Obstructive Pulmonary Disease. Hogg JC, Chu F, Utokaparch S, Woods R, Elliott WM, Buzatu L, Cherniack RM, Rogers RM, Sciurba FC, Coxson HO, Paré PD. N Engl J Med. 2004 Jun 24;350(26) : 2645-53.
  • Unplugging Mucus in Cystic Fibrosis and Chronic Obstructive Pulmonary Disease Marcus A. Mall, Ann Am Thorac Soc Vol 13, Supplement 2, pp S177–S185, Apr 2016
  • Aberrant epithelial remodeling with impairment of cilia architecture in non-cystic fibrosis bronchiectasis. Chen ZG, Li YY2, Wang ZN, Li M, Lim HF, Zhou YQ, Cai LM, Li YT, Yang LF, Zhang TT, Wang DY. J Thorac Dis. 2018 Mar;10(3):1753-1764. doi: 10.21037/jtd.2018.02.13.
  • Chest physical therapy of the distal lung. Mechanical basis of a new paradigm. G. Postiaux. Revue des Maladies Respiratoires (2014) 31, 552—567
  • Étude SIMETOL : évaluation de la tolérance et l'efficacité d'une procédure innovante de drainage bronchique assistée par Simeox® dans la mucoviscidose en alternative à la kinésithérapie respiratoire conventionnelle. P. Giovannetti, L. Morin, O. Laforgue, S. Poncet, J. Favier, M. Reynaud-Gaubert. Revue des Maladies Respiratoires, Volume 36, Supplement, 2019, Page A22
  • Pilot Safety and Feasibility Study of Simeox Physiotherapy versus traditional Physiotherapy in Adult Cystic Fibrosis Patients in Clinical Setting. E. Amelina, A. Averyanov, S.Krasovskiy. Pulmonology Congress (PTChP), Jachranaka 2018
  • The effect of chest physiotherapy with the Simeox airway clearance technology in the treatment of cystic fibrosis pulmonary exacerbation – open-label study. K. Walicka-Serzysko, M. Postek, N. Jeneralska, A. Cichocka, J. Milczewska, D. Sands. Journal of Cystic Fibrosis, Volume 18, S46 - S47
  • Benefits of Simeox airway clearance technology in non-CF patients with bronchiectasis. K. Iwan, D. Klatka, A. Gladzka, L. Morin, P. Sliwinski. American Journal of Respiratory and Critical Care Medicine 2019; 199: A5720
  • Feasibility and safety evaluation of Simeox airway clearance technique in patients with bronchiectasis. V. Kolek, P. Jakubec, J. Doleželová, L. Morin, J. Kufa. European Respiratory Journal 2019; 54: Suppl. 63, PA601
  • Effects of a new Airway Clearance Technology versus manual physiotherapy in COPD. F. Mihaltan, L. Morin, C. Borcea, A. Costantin, A. Pahontu, L. Marinescu, V. C. Cosei. ERJ 2018 52: Suppl. 62, PA4047
  • Simeox therapy in patients with COPD and Asthma. Alena Bodnarova, I Solovic. Pulmonology Congress (PTChP), Jachranaka 2018
Chapitre 15 / 24
1 h de formation